Products

SV ARB

BRAND NAME: SV ARB – 50/100

PACKING: 1x10

INDICATED IN: Heart Failure in Patients with HFrEF

Composition

  • Sacubitril 24mg + Valsartan 26mg
  • Sacubitril 49mg + Valsartan 51mg

Mode of Action

SV ARB is a combination of two drugs namely Sacubitril and Valsartan.

Sacubitril is a neprilysin inhibitor used in combination with valsartan as an adjunct to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.

Valsartan is an angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.



New HOPE in Epidemic of Heart Failure

• New Drug class, Neprilysin-angiotensin
• II receptor inhibitor, May be referred to as ‘ARNI’
• Helps patients with HFrEF stay alive and out of the hospital longer
• In PARADIGM-HF, the largest heart failure trial ever conducted, sacubitril/valsartan was proven superior to enalapril

Benefits

Sacubitril/Valsartan treatment exerts beneficial hemodynamic effects, including vasodilatation and blood volume reduction, with increased renal sodium and water excretion. It also has a beneficial effect on cardiac remodeling, improving ventricular preload and afterload.

Usage

This product is used to treat certain types of heart failure. It may help you live longer and lower your chance of having to go to the hospital for heart failure. This product contains 2 medications: sacubitril and valsartan. Sacubitril belongs to a class of drugs called neprilysin inhibitors and valsartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). They work by relaxing blood vessels so that blood can flow more easily, which makes it easier for your heart to pump blood to your body.

Precautions

warnings Alcohol

Avoid smoking and alcohol consumption.


warnings Doctor

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.


warnings Medicine

Do not take other medicines unless they have been discussed with your doctor.


warnings Liver & Kidney

Should be used with caution in patients with liver & kidney disease.